Category: Blogging

Matters of the heart: Grief, morbidity, and mortality

Matters of the heart: Grief, morbidity, and mortality

Spousal bereavement is related to an elevated threat of morbidity and mortality. Several well-regarded multidisciplinary analysis groups have sought to grasp the biopsychosocial processes underlying why widow(er)s are at elevated bodily well being threat. In this paper, we assessment analysis from a number of investigatory groups, together with our personal, exhibiting that, on common, widow(er)s exhibit maladaptive patterns of autonomic, neuroendocrine, and immune exercise in comparison with matched comparisons.

Widow(er)s additionally exhibit poorer well being behaviors than they did earlier than their partner’s loss of life. There is appreciable variation in post-loss psychological adjustment trajectories amongst widow(er)s, which seemingly corresponds to bodily well being threat trajectories.  We summarize not too long ago revealed work demonstrating the utility of attachment concept to characterize and predict particular person variations in bodily well being biomarkers; we spotlight the want for a biopsychosocial method to grasp and characterize post-loss trajectory patterns.

We conclude by discussing the risk that this line of inquiry might assist researchers, and finally suppliers, determine adjustment trajectories earlier and thus ship acceptable interventions when they’re most wanted. The coronavirus illness 19 (COVID-19) attributable to the novel coronavirus often known as SARS-CoV-2 has brought about a world public well being disaster. As of 7 January 2021, 87,640,402 confirmed circumstances and 1,891,692 mortalities have been reported worldwide.

Studies specializing in the epidemiological and medical traits of COVID-19 sufferers have advised a dysregulated immune response characterised by lymphopenia and cytokine storm in these sufferers. The exaggerated immune response induced by the cytokine storm causes septic shock, acute respiratory misery syndrome (ARDS), and/or a number of organs failure, which will increase the fatality price of sufferers with SARS-CoV-2 an infection. Yet, there may be little biobehavioral analysis on patterns of change in bodily well being threat after the loss of life of a partner.

Herein, we assessment the current analysis progress on epidemiology, medical options, and system pathology in COVID-19. Moreover, we summarized the current therapeutic methods, that are both accredited, below medical trial, and/or below investigation by the native or international well being authorities. We assume that therapies ought to give attention to the use of antiviral medicine together with immunomodulators in addition to therapy of the underlying comorbidities.

Generation of excessive yield insulin-producing cells (IPCs) from varied sources of stem cells

Type 1 diabetes mellitus happens when beta cell mass is lowered to lower than 20% of the regular stage attributable to immune system destruction of beta cell leading to an incapability to secrete sufficient insulin. The prevalence of diabetes is increasing in accordance with the American Diabetes Association and the World Health Organization (WHO), foretold to exceed 350 million by 2030. The present therapy doesn’t treatment many of the critical issues related to the illness akin to neuropathy, nephropathy, dyslipidemia, retinopathy and heart problems.

Whole pancreas or remoted pancreatic islet transplantation as a substitute remedy can stop or cut back some of the issues of diabetes. However, the scarcity of matched organ or islets cells donor and alloimmune responses restrict this therapeutic technique. Recently, a number of stories have raised extraordinarily promising outcomes to make use of totally different sources of stem cells to distinguish insulin-producing cells and give attention to the enlargement of these different sources.

Stem cells, attributable to their potential for a number of differentiation and self-renewal can differentiate into all cell sorts, together with insulin-producing cells (IPCs). Generation of new beta cells may be achieved from varied stem cell sources, together with embryonic stem cells (ESCs), grownup stem cells, akin to mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs). Thus, this chapter discusses on the help of mobile reprogramming of varied stem cells as candidates for the era of IPCs utilizing transcription elements/miRNA, cytokines/small molecules and tissue engineering.

Matters of the heart: Grief, morbidity, and mortality

Techniques and modeling of polyphenol extraction from meals: a assessment

There is a rising demand for vegetal meals having well being advantages akin to enhancing the immune system. This is due particularly to the presence of polyphenols current in small quantities in lots of fruits, greens and purposeful meals. Extracting polyphenols is difficult as a result of extraction strategies mustn’t alter meals high quality. Here, we assessment applied sciences for extracting polyphenolic compounds from meals.

Conventional strategies embrace percolation, decoction, warmth reflux extraction, Soxhlet extraction and maceration, whereas superior strategies are ultrasound-assisted extraction, microwave-assisted extraction, supercritical fluid extraction, high-voltage electrical discharge, pulse electrical area extraction and enzyme-assisted extraction. Advanced strategies are 32-36% extra environment friendly with roughly 15 occasions much less power consumption and producing higher-quality extracts.

Membrane separation and encapsulation seem promising to enhance the sustainability of separating polyphenolic compounds. We current kinetic fashions and their affect on course of parameters akin to solvent sort, strong and solvent ratio, temperature and particle measurement. Women who referred to the gynecology clinic had been evaluated and 507 girls with endometriosis (case group) had been in contrast with 520 girls with out endometriosis (management group).

COVID-19 an infection, signs, publicity, hospitalization, isolation, H1N1 an infection and vaccination, and previous medical historical past of the contributors had been recorded and in contrast between the teams utilizing IBM SPSS Statistics for Windows model 21. Endometriosis doesn’t improve the susceptibility to COVID-19 infections, however alters the manifestation of the illness.

Goat IgG, purified (serum non-immune, isotype control)
20011-5 5 mg
EUR 286
Mouse serum (non-immune/control), C57BL6
NMOS-1CS 1 ml
EUR 141
Bovine Serum Control IgG (non-immune) purified
20001-1 1 mg
EUR 141
Bovine IgG1 (Serum Control, non-immune) purified
20001-G1 100 ug
EUR 141
Bovine IgG2 (Serum Control, non-immune) purified
20001-G2 100 ug
EUR 141
Goat (non-immune) Serum IgM, purified
20011-2-1 0.5 mg
EUR 225
Human IgG, purified (serum, non-immune, isotype control)
20007-1-1 1 mg
EUR 141
Human IgG, purified (serum, non-immune, isotype control)
20007-1-100 100 mg
EUR 895
Human IgG, purified (serum, non-immune, isotype control)
20007-1-25 25 mg
EUR 651
Human IgG, purified (serum, non-immune, isotype control)
20007-1-5 5 mg
EUR 286
Mouse IgG, purified (serum non-immune, isotype control)
20008-1 1 mg
EUR 141
Mouse IgG, purified (serum non-immune, isotype control)
20008-100 100 mg
EUR 598
Mouse IgG, purified (serum non-immune, isotype control)
20008-5 5 mg
EUR 286
Rabbit IgG, purified (serum non-immune, isotype control)
20009-1 1 mg
EUR 141
Rabbit IgG, purified (serum non-immune, isotype control)
20009-25 25 mg
EUR 469
Rabbit IgG, purified (serum non-immune, isotype control)
20009-5 5 mg
EUR 286
Control Monkey Serum IgA (Rhesus, non-immune), purified
20014-1 25 ug
EUR 225
Turkey IgG, purified (non-immune, isotype control) Serum
20115-1 1 mg
EUR 141
Turkey IgM, purified (non-immune, isotype control) Serum
20115-2-1 25 ug
EUR 225
Turkey IgG, purified (non-immune, isotype control) Serum
20115-5 5 mg
EUR 225
Mouse serum (non-immune/control), C57BL6 (heat-inactivated)
NMOS-1CS-H 1 ml
EUR 164
Goat control serum (non-immunized)
NGTS-1 1 ml
EUR 110
Goat control serum (non-immunized)
NGTS-10 10 ml
EUR 164
Goat control serum (non-immunized)
NGTS-100 100 ml
EUR 286
Goat control serum (non-immunized)
NGTS-500 500 ml
EUR 529
Bovine IgG1-biotin conjugate (Serum Control, non-immune) purified
20001-G1-B 100 ug
EUR 225
Bovine IgG1-HRP conjugate (Serum Control, non-immune) purified
20001-G1-HRP 100 ug
EUR 225
Bovine IgG2-biotin conjugate (Serum Control, non-immune) purified
20001-G2-B 100 ug
EUR 225
Bovine IgG2-HRP conjugate (Serum Control, non-immune) purified
20001-G2-HRP 100 ug
EUR 225
G. Pig IgG, purified (non-immune, serum, Isotype control)
20004-1 1 mg
EUR 141
G. Pig IgM, purified (non-immune, serum, Isotype control)
20004-2-1 0.5 mg
EUR 225
G. Pig IgA, purified (non-immune, serum, Isotype control)
20004-5-1 100 ug
EUR 347
Mouse serum (non-immune/control), C57BL6 (heat-inactivated & delipidized)
NMOS-1CS-HD 1 ml
EUR 202
Ferret Serum IgM (Control, non-immune), semi-pure for ELISA
20022-1 1000 units
EUR 286
Ferret Serum IgA (Control, non-immune), semi-pure for ELISA
20023-1 1000 units
EUR 347
Positive control tissue section for each antibody; Based on availability INQUIRE
Control-Slides Set of 5
EUR 176
Donkey IgG (Control, non-immune, isotype control)
20028-1 1 mg
EUR 164
Rabbit IgG, purified (serum non-immune, isotype control), without azide, powder
20009-WA-1 1 mg
EUR 141
Rabbit IgG, purified (serum non-immune, isotype control), without azide, powder
20009-WA-5 5 mg
EUR 286
Monkey Serum IgM-biotin conjugate (Rhesus, non-immune, isotype control), purified
20013-1-B 25 ug
EUR 225
Monkey Serum IgM-biotin conjugate (Cyno., non-immune, isotype control), purified
20018-1-B 100 ug
EUR 263
Pre-immune normal rabbit serum
NRS01 200 µl
EUR 299
Goat control serum (non-immunized, non-hemolyzed, delipidized)
NGTS-10D 10 ml
EUR 141
Rabbit (non-immune) Serum IgM purified
20039-100 100 ug
EUR 164
Rabbit (non-immune) Serum IgM purified
20039-1000 1000 ug
EUR 529
Bovine IgM, purified (non-immune, serum)
20001-2-1 0.5 mg
EUR 225
Bovine IgA (non-immune, serum), purified
20001-3-1 100 ug
EUR 529
Mouse (non-immune) Serum IgM, purified
20008-2 100 ug
EUR 141
Mouse (non-immune) Serum IgG, purified
20008-25 25 mg
EUR 469
Chicken (non-immune) Serum IgM, purified
20010-2-1 0.5 mg
EUR 225
Dog (non-immune) Serum IgM, purified
20016-2-1 0.5 mg
EUR 225
Llama IgG (Control, non-immune, isotype control, ELISA grade)
20030-1 1 mg
EUR 164
Camel IgG (Control, non-immune, isotype control, ELISA grade)
20031-1 1 mg
EUR 164
Alpaca IgG (Control, non-immune, isotype control, ELISA grade)
20032-1 1 mg
EUR 164
High Control Human Serum
35-S0013H000-L4 10 ml
EUR 116
Description: High control human Serum
Low control Human Serum
35-S4321H000-L4 10 ml
EUR 116
Description: Low control human Serum
High Control Human Serum
35-S4323H000-L4 10 ml
EUR 116
Description: High control human Serum
Goat Serum
abx098258-500ml 500 ml
EUR 370
  • Shipped within 5-10 working days.
Goat Serum
abx098259-500ml 500 ml
EUR 370
  • Shipped within 5-10 working days.
Goat Immune ribonucleic acid/immune RNA ELISA kit
E06I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Immune ribonucleic acid/immune RNA ELISA kit
E06I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Immune ribonucleic acid/immune RNA ELISA kit
E06I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat control serum (non-immunized, non-hemolyzed, heat-inactivated)
NGTS-10H 10 ml
EUR 141
Monkey Serum IgM (Rhesus, non-immune), purified
20013-1 50 ug
EUR 164
Rat IgM (non-immune), purified (isotype control)
20005-2-1 0.1 mg
EUR 164
Rat IgA (non-immune), purified (isotype control)
20005-3-1 25 ug
EUR 225
Rabbit IgM (isotype control, non-immune), purified
20009-2-1 0.1 mg
EUR 164
Rabbit IgA (isotype control, non-immune), purified
20009-3-1 0.1 mg
EUR 286
Chimpanzee IgG (non-immune, isotype control), purified
20012-Ch-1 1 mg
EUR 225
Donkey IgG (non-immune, isotype control), purified
20015-1 1 mg
EUR 141
Dog IgG (isotype control, non-immune), purified
20016-1 1 mg
EUR 141
Dog IgM (isotype control, non-immune), purified
20016-2-1-B 0.1 mg
EUR 225
Dog IgE (isotype control, non-immune), purified
20016-3-1 10 ug
EUR 225
Horse IgA (Equine, control, non-immune), purified
20019-3-100 100 ug
EUR 286
Mouse IgG1k (non-immune, isotype control), purified
20101-1 1 mg
EUR 286
Baboon IgG (non-immune, isotype control), purified
20118-1 1 mg
EUR 202
Baboon IgG (non-immune, isotype control), purified
20118-10 10 mg
EUR 895
Bat IgG (non-immune, isotype control), purified
20121-1 25 ug
EUR 286
Human RF Control Serum Protein
abx060707-2ml 2 ml
EUR 384
  • Shipped within 5-10 working days.
Mouse control serum, Balb/c
NMOS-5BS 5 ml
EUR 164
Mouse control serum, CD-1
NMOS-CD1-1 1 ml
EUR 103
Mouse control serum, CD-1
NMOS-CD1-5 5 ml
EUR 164
Chicken control serum (non-immunized)
NCHS-10 10 ml
EUR 286
Chicken control serum (non-immunized)
NCHS-100 100 ml
EUR 529
Chicken control serum (non-immunized)
NCHS-500 500 ml
EUR 773
Chimpanzee control serum, (IgG's-depleted)
NCMS-DG-1 1 ml
EUR 225
Goat Anti-Adenovirus Hexon Protein (hxn) IgG negative control serum
950-160-07N 1 ml
EUR 164
Goat Anti-Adenovirus Hexon Protein (hxn) IgG positive control serum
950-160-08P 1 ml
EUR 225
Goat control serum (non-immunized, non-hemolyzed, delipidized, heat-inactivated)
NGTS-10DH 10 ml
EUR 164
Ferret IgG (Control, non-immune, isotype control), semi-pure for ELISA
20021-1 100 ug
EUR 225
Elk IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20024-1 100 ug
EUR 225
Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20024-2 100 ug
EUR 225
Bison IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20025-1 100 ug
EUR 225
Raccoon IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20026-1 100 ug
EUR 225
Skunk IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20027-1 100 ug
EUR 225
Goat Serum (Sterile)
20-abx800034
  • EUR 606.00
  • EUR 773.00
  • EUR 439.00
  • 100 ml
  • 500 ml
  • 50 ml
  • Shipped within 1-5 working days.
Goat Serum (Sterile)
abx800034-1L 1 L
EUR 926
  • Shipped within 1-5 working days.
Normal Goat Serum
9067 50 ml
EUR 100.75
Description: Normal Goat Serum
Normal Goat Serum
88-B9999G000-S0 10 ml
EUR 133
Description: Control Normal Goat serum
Normal Goat Serum
88-NG22 500 ml
EUR 30
Description: Control Normal Goat Serum
Normal Goat Serum
88-NG22S 500 ml
EUR 191
Description: Control Normal Goat Serum
Normal Goat Serum
88R-1006 10 ml
EUR 182
Description: Normal Goat Serum which has been lipid extracted and dialyzed against 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Normal Goat Serum
88R-NG001 50 ml
EUR 117
Description: Normal Goat Serum for use as a control or blocking reagent
Goat Serum Albumin
30R-3305 10 mg
EUR 257
Description: Purified native Goat Serum Albumin
Goat Serum antibody
20-S1121G000-V0 10 ml
EUR 133
Description: Guinea pig polyclonal Goat Serum antibody
Goat Serum antibody
20-S1121GN00-D0 10 ml
EUR 133
Description: Guinea pig polyclonal Goat Serum antibody
Goat IgG Control
GT15900 1 mg
EUR 166
Goat IgG control
31R-AG001 1 mg
EUR 127
Description: Goat Immunoglobulins Goat IgG control
Hamster (Syrian, non-immune) Serum IgM, purified (Syrian)
20003-2-1 0.5 mg
EUR 225
Bactrian camel (Camelus bactrianus; normal, non-immune) serum
NBCS-1 1 ml
EUR 286
Bovine IgM-Biotin Conjugate (control, non-immune), purified
20001-2-1-B 0.1 mg
EUR 225
Cat IgG, unlabeled (non-immune, isotype control) purified
20002-1-UL 1 mg
EUR 164
Cat IgM, unlabeled (non-immune, isotype control) purified
20002-5-UL 0.1 mg
EUR 164
Rat IgG, purified (Whole, non-immune) (isotype control)
20005-1 1 mg
EUR 141
Rat IgG, purified (Whole, non-immune) (isotype control)
20005-10 10 mg
EUR 408
Sheep IgM-Biotin Conjugate (non-immune) control, purified
20006-2-B 0.1 mg
EUR 225
Chicken IgG unlabeled (isotype control, non-immune), purified
20010-1 1 mg
EUR 141
Monkey IgG (Rhesus, non-immune, isotype control), purified
20012-1 1 mg
EUR 202
Squirrel Monkey IgG (non-immune, isotype control), purified
20012-1-SM 100 ug
EUR 164
Monkey IgG (Rhesus, non-immune, isotype control), purified
20012-10 10 mg
EUR 895
Monkey IgA (Rhesus, non-immune, isotype control), purified
20012-2-1 25 ug
EUR 225
Donkey IgG (non-immune, isotype control) IgG, purified
20015-10 10 mg
EUR 286
Donkey IgM (unlabeled, non-immune, isotype control) purified
20015-2-1 0.1 mg
EUR 164
Pig IgG (swine non-immune, isotype control), purified
20017-1 1 mg
EUR 141
Pig IgM (swine non-immune, isotype control), purified
20017-2-1 0.5 mg
EUR 225
Pig IgA (swine non-immune, isotype control), purified
20017-4-1 25 ug
EUR 225
Monkey IgG (Cynomolgous, non-immune, isotype control), purified
20018-1 1 mg
EUR 202
Monkey IgG (Cynomolgous, non-immune, isotype control), purified
20018-10 10 mg
EUR 895
Monkey (Cynomolgus) control serum (IgG's-depleted)
NMCS-DG-1 1 ml
EUR 225
Goat Circulating Immune Complexes ELISA kit
E06C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Circulating Immune Complexes ELISA kit
E06C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Circulating Immune Complexes ELISA kit
E06C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Bovine IgG-Biotin conjugate (non-immune, isotype control) purified
20001-1-B 0.5 mg
EUR 225
Bovine IgG-FITC conjugate (non-immune, isotype control) purified
20001-1-F 0.5 mg
EUR 225
Bovine IgG-HRP conjugate (non-immune, isotype control) purified
20001-1-HP 0.5 mg
EUR 225
Bovine IgG Fc, unlabeled (non-immune, isotype control) purified
20001-2-UL 0.1 mg
EUR 164
Bovine IgG Fab, unlabeled (non-immune, isotype control) purified
20001-3-UL 0.1 mg
EUR 164
Bovine IgG Fab2, unlabeled (non-immune, isotype control) purified
20001-4-UL 0.1 mg
EUR 164
Cat IgG-Biotin conjugate (non-immune, isotype control) purified
20002-1-B 0.5 mg
EUR 225
Cat IgG-FITC conjugate (non-immune, isotype control) purified
20002-1-F 0.5 mg
EUR 225
Cat IgG-HRP conjugate (non-immune, isotype control) purified
20002-1-HP 0.1 mg
EUR 225
Cat IgG Fc, unlabeled (non-immune, isotype control) purified
20002-2-UL 0.1 mg
EUR 164
Cat IgG Fab, unlabeled (non-immune, isotype control) purified
20002-3-UL 0.1 mg
EUR 164
Cat IgG Fab2, unlabeled (non-immune, isotype control) purified
20002-4-UL 0.1 mg
EUR 164
Cat IgM-Biotin conjugate (non-immune, isotype control) purified
20002-5-B 0.1 mg
EUR 225
Sheep IgG-Biotin Conjugate (isotype control, non-immune), purified
20006-1-B 0.5 mg
EUR 202
Sheep IgG-FITC Conjugate (isotype control, non-immune), purified
20006-1-F 0.5 mg
EUR 202
Sheep IgG-HRP Conjugate (isotype control, non-immune), purified
20006-1-HP 0.5 mg
EUR 202
Sheep IgG Fc unlabeled (isotype control, non-immune), purified
20006-4-UL 0.5 mg
EUR 202
Human IgG-Biotin conjugate (isotype control, non-immune), purified
20007-1-B 0.5 mg
EUR 225
Human IgG-FITC conjugate (isotype control, non-immune), purified
20007-1-F 0.5 mg
EUR 225
Human IgM (myeloma, >96%, non-immune, control; bulk size)
20007-2-B-100 100 mg Ask for price
Human IgM (myeloma, >96%, non-immune, control; bulk size)
20007-2-B-1000 1000 mg Ask for price
Rabbit IgG (non-immune, isotype control, CHIP/IP grade)
20009-1-CH 100 ug
EUR 225
Rabbit IgM-Biotin Conjugate (isotype control, non-immune), purified
20009-2-1-B 0.1 mg
EUR 225
Rabbit IgM-FITC Conjugate (isotype control, non-immune), purified
20009-2-1-F 0.1 mg
EUR 225
Rabbit IgM-HRP Conjugate (isotype control, non-immune), purified
20009-2-1-HP 0.1 mg
EUR 225
Rabbit IgA-Biotin Conjugate (isotype control, non-immune), purified
20009-3-1-B 0.1 mg
EUR 408
Rabbit IgA-FITC Conjugate (isotype control, non-immune), purified
20009-3-1-F 0.1 mg
EUR 408
Rabbit IgA-HRP Conjugate (isotype control, non-immune), purified
20009-3-1-HP 0.1 mg
EUR 408
Chicken IgG-Biotin conjugate (isotype control, non-immune), purified
20010-1-B 0.5 mg
EUR 225

The prevalence of the illness could depend upon the interplay between the virus and the particular person’s immune system however additional research are required on this regard. In at present’s world, coronavirus illness 2019 (COVID-19) is the most crucial well being downside and analysis is sustained on finding out the related elements. But it isn’t clear whether or not endometriosis will increase the threat of COVID-19.

Corticosteroids Use in Pregnant Women with COVID-19: Recommendations from Available Evidence

Corticosteroids Use in Pregnant Women with COVID-19: Recommendations from Available Evidence

Pregnant ladies expertise immune system modifications to accommodate and tolerate the rising foetus, these modifications additionally enhance their susceptibility to viral infections similar to SARS-COV-2. COVID-19 in being pregnant will increase the probability of hospital admission and intensive care in comparison with non-pregnant ladies. Early administration of low-dose corticosteroids to sufferers with acute respiratory misery syndrome can scale back all-cause mortality amongst such sufferers.

However, throughout being pregnant, extended use of corticosteroids that readily cross the placenta like dexamethasone can negatively influence each the mom and foetus. Evidence is thus wanted on the selection, timing, and length for corticosteroids use amongst pregnant ladies with COVID-19. This article goals to supply proof on corticosteroid use in pregnant ladies with COVID-19. The RECOVERY trial deduced that low-dose dexamethasone (6 milligrams) lowered mortality by as much as one-third amongst COVID-19 sufferers on mechanical air flow and one-fifth amongst those that acquired supplemental oxygen.

Pregnant ladies in this trial acquired both oral prednisolone or intravenous hydrocortisone. Based on the RECOVERY trial findings, the Royal College of Obstetricians and Gynaecologists (RCOG) recommends that pregnant ladies with moderate-to-severe COVID-19 obtain oral prednisolone or intravenous hydrocortisone. However, at the moment, the World Health Organisation (WHO) doesn’t explicitly specify which corticosteroid to make use of amongst pregnant ladies with moderate-to-severe COVID-19.

We additionally word that there aren’t any revealed articles on corticosteroid use amongst pregnant ladies with extreme COVID-19 in Africa. After demonstrating the flexibility of the vaccine to elicit Th1 and Th2 immune responses and observing its good security in mouse a mannequin, the robust in vitro bactericidal exercise and prophylactic results of the conjugate vaccine in opposition to an infection had been additional demonstrated by evaluating post-infection tissue bacterial hundreds, observing suppressed serum pro-inflammatory cytokine ranges.

Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex

Complement, contact activation, coagulation, and fibrinolysis are serum protein cascades that want strict regulation to take care of human well being. Serum glycoprotein, a C1 inhibitor (C1-INH), is a key regulator (inhibitor) of serine proteases of all of the above-mentioned pathways. Recently, an autotransporter protein, virulence-associated gene 8 (Vag8), produced by the whooping cough pathogen, Bordetella pertussis, was proven to bind to C1-INH and intrude with its perform.

Here, we current the construction of the Vag8-C1-INH complicated decided utilizing cryo-electron microscopy at a 3.6-Å decision. The construction exhibits a novel mechanism of C1-INH inhibition not employed by different pathogens, the place Vag8 sequesters the reactive heart loop of C1-INH, stopping its interplay with the goal proteases.

The construction of a 10-kDa protein complicated is without doubt one of the smallest to be decided utilizing cryo-electron microscopy at excessive decision. The construction reveals that C1-INH is sequestered in an inactivated state by burial of the reactive heart loop in Vag8. By so doing, the bacterium is ready to concurrently perturb the various pathways regulated by C1-INH. Virulence mechanisms such because the one described right here assume extra significance given the rising proof about dysregulation of contact activation, coagulation, and fibrinolysis resulting in COVID-19 pneumonia.

Additionally, the broad safety from the vaccine was additional proved by way of deadly problem with A. baumannii. Overall, these outcomes indicated that the conjugate vaccine may elicit an environment friendly immune response and supply good safety in opposition to A. baumannii an infection in murine sepsis fashions. Thus, the conjugate vaccine may be thought of as a promising candidate vaccine for stopping A. baumannii an infection. In this research, we created a conjugate vaccine in opposition to A. baumannii by introducing an O-linked glycosylation system into the host pressure.

Corticosteroids Use in Pregnant Women with COVID-19: Recommendations from Available Evidence

The Mnemonic Tuning for Contamination: A Replication and Extension Study Using More Ecologically Valid Stimuli

To face threats posed by pathogens, pure choice designed the Behavioral Immune System, which orchestrates a number of responses aimed to forestall contact with pathogens. Memory appears to reinforce this system. Using line drawings of objects, earlier research discovered that objects described as having been touched by sick folks had been higher remembered than these described as having been touched by well beingy folks.

The present work was designed to duplicate and prolong these preliminary research utilizing extra ecologically-valid stimuli-photographs of actual objects being held by arms. These pictures had been proven alongside with descriptors (Experiment 1a) or faces (Experiment 1b) denoting the well being standing of the individual whose arms had been holding the objects. Experiments 2 and three used, as cues of contamination, soiled arms coated with a substance described as being vomit and diarrhea, respectively.

Experiment Three additionally investigated the necessity for a fitness-relevant context for the mnemonic impact to happen. In all experiments, stimuli had been offered individually on the display with the “contamination cue.” During encoding individuals needed to establish whether or not every object had been touched by a sick or a well beingy individual. The outcomes of the ultimate shock free recall duties replicated these beforehand reported: efficiency was enhanced for objects encoded as potential sources of contamination.

Goat Immune ribonucleic acid/immune RNA ELISA kit

E06I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Immune ribonucleic acid/immune RNA ELISA kit

E06I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Immune ribonucleic acid/immune RNA ELISA kit

E02I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Immune ribonucleic acid/immune RNA ELISA kit

E02I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Immune ribonucleic acid/immune RNA ELISA kit

E02I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Immune ribonucleic acid/immune RNA ELISA kit

E01I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Immune ribonucleic acid/immune RNA ELISA kit

E01I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Immune ribonucleic acid/immune RNA ELISA kit

E01I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Immune ribonucleic acid/immune RNA ELISA kit

E03I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Immune ribonucleic acid/immune RNA ELISA kit

E03I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Immune ribonucleic acid/immune RNA ELISA kit

E03I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Immune ribonucleic acid/immune RNA ELISA kit

E04I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Immune ribonucleic acid/immune RNA ELISA kit

E04I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Immune ribonucleic acid/immune RNA ELISA kit

E04I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Immune ribonucleic acid/immune RNA ELISA kit

E08I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Immune ribonucleic acid/immune RNA ELISA kit

E08I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Immune ribonucleic acid/immune RNA ELISA kit

E08I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Immune ribonucleic acid/immune RNA ELISA kit

E07I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Immune ribonucleic acid/immune RNA ELISA kit

E07I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Immune ribonucleic acid/immune RNA ELISA kit

E07I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Immune ribonucleic acid/immune RNA ELISA kit

E09I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Immune ribonucleic acid/immune RNA ELISA kit

E09I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Immune ribonucleic acid/immune RNA ELISA kit

E09I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Immune ribonucleic acid/immune RNA ELISA kit

E05I0405-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Immune ribonucleic acid/immune RNA ELISA kit

E05I0405-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Immune ribonucleic acid/immune RNA ELISA kit

E05I0405-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Immune ribonucleic acid/immune RNA in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Immune ribonucleic acid/immune RNA(iRNA)ELISA Kit

GA-E1645HM-48T 48T
EUR 289

Human Immune ribonucleic acid/immune RNA(iRNA)ELISA Kit

GA-E1645HM-96T 96T
EUR 466

Human Immune ribonucleic acid/immune RNA,iRNA ELISA Kit

201-12-1629 96 tests
EUR 440
  • This Immune ribonucleic acid/immune RNA ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Immune ribonucleic acid/immune RNA(iRNA)ELISA Kit

QY-E02187 96T
EUR 413

Chicken Immune RNA,Irna ELISA Kit

CN-00824C1 96T
EUR 441

Chicken Immune RNA,Irna ELISA Kit

CN-00824C2 48T
EUR 291

Human Immune RNA,Irna ELISA Kit

CN-04542H1 96T
EUR 444

Human Immune RNA,Irna ELISA Kit

CN-04542H2 48T
EUR 294

Chicken Immune RNA,Irna ELISA Kit

QY-E80070 96T
EUR 426

Green RNA Lysis Kit 50

GREENE1-RNA 50pack
EUR 180
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250

GREENE5-RNA 250pack
EUR 571
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Navy RNA Lysis Kit 50

NAVYE1-RNA 50pack
EUR 198
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250

NAVYE5-RNA 250pack
EUR 651
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Pink RNA Lysis Kit 50

PINKE1-RNA 50pack
EUR 178
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250

PINKE5-RNA 250pack
EUR 561
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50

REDE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250

REDE5-RNA 250pack
EUR 622
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50

YELLOWE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250

YELLOWE5-RNA 250pack
EUR 624
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E GREEN RNA Lysis Kit 100

GREEN5E100-RNA 100pack
EUR 386
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20

GREEN5E20-RNA 20pack
EUR 138
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50

GREENR1-RNA 50pack
EUR 184
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250

GREENR5-RNA 250pack
EUR 587
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E Navy RNA Lysis Kit 100

NAVY5E100-RNA 100pack
EUR 453
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20

NAVY5E20-RNA 20pack
EUR 153
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50

NAVYR1-RNA 50pack
EUR 202
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250

NAVYR5-RNA 250pack
EUR 666
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

5E PINK RNA Lysis Kit 100

PINK5E100-RNA 100pack
EUR 380
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20

PINK5E20-RNA 20pack
EUR 136
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50

PINKR1-RNA 50pack
EUR 181
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250

PINKR5-RNA 250pack
EUR 576
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100

RED5E100-RNA 100pack
EUR 429
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20

RED5E20-RNA 20pack
EUR 148
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50

REDR1-RNA 50pack
EUR 195
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250

REDR5-RNA 250pack
EUR 638
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 50

YELLOWR1-RNA 50pack
EUR 199
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250

YELLOWR5-RNA 250pack
EUR 656
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed

ELISA-1 1
EUR 202

Goat Circulating Immune Complexes ELISA kit

E06C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Circulating Immune Complexes ELISA kit

E06C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Circulating Immune Complexes ELISA kit

E06C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circulating Immune Complexes ELISA kit

E02C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circulating Immune Complexes ELISA kit

E02C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Circulating Immune Complexes ELISA kit

E02C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circulating Immune Complexes ELISA kit

E03C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circulating Immune Complexes ELISA kit

E03C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Circulating Immune Complexes ELISA kit

E03C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circulating Immune Complexes ELISA kit

E04C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circulating Immune Complexes ELISA kit

E04C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Circulating Immune Complexes ELISA kit

E04C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Circulating Immune Complexes ELISA kit

E01C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Circulating Immune Complexes ELISA kit

E01C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Circulating Immune Complexes ELISA kit

E01C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circulating Immune Complexes ELISA kit

E07C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circulating Immune Complexes ELISA kit

E07C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Circulating Immune Complexes ELISA kit

E07C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circulating Immune Complexes ELISA kit

E09C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circulating Immune Complexes ELISA kit

E09C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Circulating Immune Complexes ELISA kit

E09C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Circulating Immune Complexes ELISA kit

E08C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Circulating Immune Complexes ELISA kit

E08C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Circulating Immune Complexes ELISA kit

E08C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Frit Kit

FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Guinea pig Circulating Immune Complexes ELISA kit

E05C0241-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Circulating Immune Complexes ELISA kit

E05C0241-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Circulating Immune Complexes ELISA kit

E05C0241-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Circulating Immune Complexes in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human circulating immune complex(CIC)ELISA Kit

GA-E0366HM-48T 48T
EUR 289

Human circulating immune complex(CIC)ELISA Kit

GA-E0366HM-96T 96T
EUR 466

Mouse Circulating Immune Complexes (CIC) ELISA Kit

abx255266-96tests 96 tests
EUR 707
  • Shipped within 5-12 working days.

Monkey circulating immune complex (CIC) ELISA Kit

abx255348-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.

Human circulating immune complex (CIC) ELISA Kit

abx252198-96tests 96 tests
EUR 754
  • Shipped within 5-12 working days.

Human circulating immune complex,CIC ELISA Kit

201-12-0350 96 tests
EUR 440
  • This circulating immune complex ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Dog circulating immune complex (CIC) ELISA kit

CSB-EQ027971DO-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Dog circulating immune complex (CIC) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Dog circulating immune complex (CIC) ELISA kit

1-CSB-EQ027971DO
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Dog circulating immune complex (CIC) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Monkey circulating immune complex(CIC)ELISA Kit

CSB-E15098Mk-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Monkey circulating immune complex (CIC) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Monkey circulating immune complex(CIC)ELISA Kit

1-CSB-E15098Mk
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Monkey circulating immune complex(CIC) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse circulating immune complex(CIC)ELISA Kit

CSB-E16553m-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse circulating immune complex (CIC) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse circulating immune complex(CIC)ELISA Kit

1-CSB-E16553m
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse circulating immune complex(CIC) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat circulating immune complex(CIC)ELISA Kit

CSB-E17938r-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat circulating immune complex (CIC) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat circulating immune complex(CIC)ELISA Kit

1-CSB-E17938r
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Rat circulating immune complex(CIC) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human ciFAulating immune complex,CIC ELISA Kit

CN-04046H1 96T
EUR 468

Human ciFAulating immune complex,CIC ELISA Kit

CN-04046H2 48T
EUR 318

Human circulating immune complex(CIC)ELISA Kit

QY-E00584 96T
EUR 361

Monkey circulating immune complex,CIC ELISA Kit

QY-E110086 96T
EUR 439

CIC ELISA Kit| Monkey circulating immune complex ELISA Kit

EF012690 96 Tests
EUR 689

CIC ELISA Kit| Mouse Circulating Immune Complexes ELISA Kit

EF012818 96 Tests
EUR 689

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266

Orange Lysis Kit 50

ORANGEE1-RNA 50pack
EUR 165
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange Lysis Kit 250

ORANGEE5-RNA 250pack
EUR 537
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 50

ORANGER1-RNA 50pack
EUR 169
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 50, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Orange RINO Lysis Kit 250

ORANGER5-RNA 250pack
EUR 554
Description: Bead lysis kits for extracting bacteria or generating single cell suspensions from tissue samples. Pack of 250, 1.5mL RINO tubes prefilled with stainless steel beads. RNase free.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Goat Low density lipoprotein immune complex ELISA kit

E06L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Low density lipoprotein immune complex ELISA kit

E06L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Goat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Low density lipoprotein immune complex ELISA kit

E06L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Goat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Low density lipoprotein immune complex ELISA kit

E02L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Low density lipoprotein immune complex ELISA kit

E02L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Low density lipoprotein immune complex ELISA kit

E02L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rat Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Low density lipoprotein immune complex ELISA kit

E03L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Low density lipoprotein immune complex ELISA kit

E03L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Low density lipoprotein immune complex ELISA kit

E03L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Mouse Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Low density lipoprotein immune complex ELISA kit

E01L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Low density lipoprotein immune complex ELISA kit

E01L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Low density lipoprotein immune complex ELISA kit

E01L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Low density lipoprotein immune complex ELISA kit

E04L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Low density lipoprotein immune complex ELISA kit

E04L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Low density lipoprotein immune complex ELISA kit

E04L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Rabbit Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human low density lipoprotein immune complex ELISA Kit

ELA-E0803h 96 Tests
EUR 824

Dog Low density lipoprotein immune complex ELISA kit

E08L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Canine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Low density lipoprotein immune complex ELISA kit

E08L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Low density lipoprotein immune complex ELISA kit

E08L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Canine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Low density lipoprotein immune complex ELISA kit

E07L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Porcine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Low density lipoprotein immune complex ELISA kit

E07L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Low density lipoprotein immune complex ELISA kit

E07L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Porcine Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Low density lipoprotein immune complex ELISA kit

E09L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Low density lipoprotein immune complex ELISA kit

E09L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Low density lipoprotein immune complex ELISA kit

E09L0216-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Monkey Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

RNA Kit

20-abx098089
  • EUR 105.00
  • EUR 342.00
  • 2 rxns
  • 50 rxns
  • Shipped within 5-10 working days.

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153
  • Category: Cas9

IgE (Immune globulin E) ELISA test

21 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of IgE (Immune globulin)

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941
  • Category: PinPoint Integrase Tools

Guinea pig Low density lipoprotein immune complex ELISA kit

E05L0216-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Low density lipoprotein immune complex ELISA kit

E05L0216-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Guinea pig Low density lipoprotein immune complex in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Furthermore, the outcomes of the final research reinstate the significance of fitness-relevance for the impact to happen. These outcomes set up the generality of the contamination impact beforehand discovered, now utilizing extra ecologically-valid stimuli. Acinetobacter baumannii poses a severe menace to human well being, primarily due to its widespread distribution and extreme drug resistance. However, no licensed vaccines exist for this pathogen.

Tips To Validate The Antibodies

The antibodies are one of the most widely used tools in research laboratories to identify, isolate or block various molecules. Due to the specificity assumed, it is essential to validate the antibodies for use in each of the techniques in which they are going to be applied, since, as we have seen on other occasions, an antibody can be very specific, for example in an ELISA immunoassay , and yet give a very weak signal in other types of tests such as Western Blot .

Validating the antibodies implies testing the following aspects:

  • Antibody specificity in the selected technique
  • Affinity for antigen
  • Reproducibility between trials

In this post we collect some tips to guide you when validating the antibodies and defining their specificity.

Main Problems With Antibodies, How To Solve Them?

The most common problems that arise from the use of antibodies are cross-reactivity, variability between batches and their application in an incorrect technique.

1.- CROSS REACTIVITY

  • Problem: Antibodies not only bind to the target antigen, but also to other proteins present in the sample.

2.- VARIABILITY BETWEEN LOTS

  • Problem: It is more frequent in the case of polyclonal antibodies, since the same antibody produced in different animals could work slightly differently.

3.- WRONG APPLICATION

  • Problem: The different techniques and experimental conditions in which each one is carried out can modify the folding of the target protein, and consequently, its ability to bind to the antibody.

To avoid any of these problems, it is vitally important to validate the antibodies before use.

But how do you do it? Pay attention to the trials we list below.

Assays To Validate The Antibodies

Antibodies can be validated by a multitude of functional tests, each of which has its advantages and disadvantages:

ELISA

  • Pros:
    • Quantitative test, allows confirmation of sensitivity.
    • High performance assay, a high number of samples can be processed simultaneously.
  • Cons:
    • It does not determine whether the antibody can lead to cross reactivity.

WESTERN BLOT (WB)

  • Pros:
    • Qualitative test, easy and simple to carry out.
    • Ideal for denatured proteins.
  • Cons:
    • Difficult to optimize.
    • It takes a lot of time.
    • Only a few antibodies can be tested at the same time.

IMMUNOHISTOCHEMISTRY (IHC) / IMMUNOCYTOCHEMISTRY (ICC)

  • Pros:
    • Relatively low-cost techniques.
    • Qualitative test.
  • Cons:
    • Difficult to standardize.
    • The accessibility of epitopes can vary in fixed tissues.
    • It does not determine whether the antibody non-specifically recognizes other proteins with the same cell location.

FLOW CYTOMETRY (FC)

  • Pros:
    • High performance assay, a high number of samples can be processed simultaneously.
    • Easy to optimize.
  • Cons:
    • It does not determine whether the antibody can lead to cross reactivity.

KNOCKDOWN siRNA

  • Pros:
    • KnockDown cell lines can be used in all assays: WB, IHC / ICC, FC …
  • Cons:
    • KnockDown is transitory.
    • Difficult to optimize.

KNOCKOUT CELL LINES (KO)

  • Pros:
    • They guarantee that there will be no expression of the target gene, so they are excellent negative controls, guaranteeing the specificity of the antibody.
    • They can be used in all tests: WB, IHC / ICC, FC …
  • Cons:
    • KnockOut cell lines against specific genes are not always viable.

MASS SPECTROMETRY (MS)

  • Pros:
    • High performance assays, a high number of samples can be processed simultaneously.
  • Cons:
    • Requires the use of a mass spectrometer and qualified personnel.
    • Difficult to optimize.

Other Considerations To Take Into Account To Validate The Antibodies

1.- The choice and preparation of cell lines or tissue samples , using the corresponding positive and negative controls, and taking into account whether the antibody recognizes the protein in its native or denatured form.

2.- The protocols , paying special attention and optimizing the incubation times individually (very short periods can affect sensitivity, and on the contrary, excessive incubation times could result in background noise problems), dilutions of work, blocking conditions, etc.

3.- The choice of buffers , determining the optimum in each case.

Ionic Channels And Cancer Immunology

The ion channels are membrane proteins that control the passage of ions therethrough in response to different stimuli. The dysregulation and / or dysfunction of these ion channels is related to a multitude of diseases, including cancer.

Cancer development depends on the effectiveness of the immune system in destroying tumor cells, and the key steps in this process are regulated by various ion channels .

These channels can affect the activation of immune cells and their toxicity against cancer, making them a more than interesting target for research and development of new antitumor therapies.

The Role Of Ion Channels In Cancer Immunology

Tumor cells are recognized by the immune system through the specific antigens they express on their surface, and through joint and integrated action between innate and adaptive immunity mechanisms, these cancer cells are killed. But some of them are capable of developing mechanisms to reduce their immunogenicity, and therefore, not to be recognized by the immune system and thus avoid their eradication.

Strategies to enhance anti-cancer immunity could be directed towards increasing efficiency in antigen presentation, recognition and elimination of tumor cells by the immune system, or inhibition of tumor-induced immunosuppression. Ionic channels play a fundamental role in any of these processes, as the following examples show:

  • Lysis of tumor cells by CD8 + cytotoxic T cells is mediated by Ca2 + Kv1.3 and KCa3.1 ion channels.
  • Lack of functional Ca2 + channels inhibits the development of regulatory T cells.
  • Blocking the KCa3.1 ion channels increases cytotoxicity and lysis of tumor cells by NK cells.

For all these reasons, the network of ion channels present in immune cells that regulate both innate and adaptive immune responses are highly interesting targets in the development of new therapeutic tools against cancer.

Tumor Processes And Ion Channels

Some of the tumor processes in which the active participation of ion channels has been described are the following:

  • Cell cycle progression and proliferation

Ionic transport is an integral part of the regulation of cell cycle progression and proliferation.

  • Apoptosis

Ionic fluxes are also crucial in the regulation of programmed cell death pathways.

  • Metabolism of tumor cells and tumor microenvironment

The cellular microenvironment usually presents different physical-chemical characteristics than most normal tissues and contains different types of cells in addition to tumor cells. Ionic channels are essential in the interaction between tumor cells and their microenvironment.

  • Tumor cell motility and invasiveness

The motility and invasion of tumor cells, the main steps in metastasis, require the functional integration of several processes, almost all of them regulated by ion channels.

Antibodies For Ion Channel Research

Specific antibodies against ion channels are a fundamental research tool for the study of cancerous phenomena of proliferation, migration and metastasis, angiogenesis and resistance to apoptosis.

Here we leave you a selection of antibodies for the investigation of ion channels (IC)  from the Genetex company .

1.- PROLIFERATION

C. I.AntibodiesApplicationsReference
Shaker-like K + channelsKv1.1 antibodyICC / IF, WBGTX54875
Kv1.5 antibodyICC / IF, IHC, IP, WBGTX54837
EAG-related K + channelsKv11.1 antibodyICC / IF, IHC, IP, WBGTX54776
Kv11.1 antibodyICC / IF, IHC, IP, WBGTX54785
Kv11.1 antibodyFACS, ICC / IF, IHC, IP, WBGTX54789
Ca2 + activated K + channelsKCA3.1 / KCNN4 antibodyICC / IF, IHC, IP, WBGTX54786
TRPTRPC6 antibodyFACS, ICC / IF, IHC, IP, WBGTX54757
TRPM7 antibodyICC / IF, IHC, IHC-P, WBGTX54865
TRPM8 antibodyICC / IF, IHC, IHC-Fr, IP, WBGTX54866
P2XP2X7 antibodyICC / IF, IHC, IHC-P, IP, WBGTX54794
SOCsORAl1 antibodyFACS, WBGTX54826

2.- MIGRATION AND METASTASIS

CIAntibodiesApplicationsReference
EAG K + channelsKv10.1 antibodyICC / IF, IHC, WBGTX54788
Kir channelsKir3.1 / GIRK1 antibodyICC / IF, IHC, IP, WBGTX54831
TRPTRPM7 antibodyICC / IF, IHC, IHC-P, WBGTX54865
TRPM8 antibodyICC / IF, IHC, IHC-Fr, IP, WBGTX54866
TRPV1 antibodyICC / IF, IHC, WBGTX54762
P2XP2X7 antibodyICC / IF, IHC, IHC-P, IP, WBGTX54794
SOCsORAl1 antibodyFACS, WBGTX54826

3.- TUMORAL ANGIOGENESIS

CIAntibodiesApplicationsReference
TRPTRPC6 antibodyFACS, ICC / IF, IHC, IP, WBGTX54757
SOCsORAl1 antibodyFACS, WBGTX54826

4.- RESISTANCE TO APOPTOSIS

CIAntibodiesApplicationsReference
TRPTRPA1 antibodyICC / IF, IHC, IP, WBGTX54765
P2XP2X7 antibodyICC / IF, IHC, IHC-P, IP, WBGTX54794
SOCsORAl1 antibodyFACS, WBGTX54826

In addition to GENETEX , other of our represented houses also offer specific antibodies against ion channels . You can check the list of each of them by clicking on the links that we leave you below:

COVALAB (+ info)

  • Antibodies to COVALAB ion channels

LSBIO (+ info)

  • Antibodies to LSBIO ion channels

PROSCI (+ info)

  • Antibodies to PROSCI ion channels

ST. JOHN´S LAB (+ info)

  • Antibodies against ion channels of ST JOHN´s LAB

ORIGIN (+ info)

  • Antibodies to ion channels OriGene

Coxiella burnetii – how deadly could be the Q fever?

  1. What is this Coxiella pathogen?

Coxiella burnetii is a Gram-negative bacterium that infects animals and humans causing the Q fever (query fever). This is a strictly intracellular pathogen that encodes several basic proteins and buffers to acidic pH the environment of the phagolysosome-like vacuole. The genome of this bacterium includes 4 Na+ exchangers and transporters for molecules that protect the cells from osmotic and oxidative stress.

The Coxiella’s life cycle contains 2 forms of development – large-cell (LCV) or the active replicating form found during the log phase and small-cell variant (SCV) that are typical for the stationary phase. SCVs show a significant resistance to various stressful factors of the environment – mechanical, heat, chemical, changes in the osmotic levels. Many reports describe the survival of the Coxiella cells on wool at room temperature for up to 1 year, in milk for more than 3 years, and in fresh meat for 4 weeks. The Coxiella burnetii is characterized as highly virulent and can be transmitted by aerosols. Due to this, U.S. Centers for Disease Control and Prevention categorized this pathogenic agent as Class B bacteria. The infection is not observed with high death rate, but it can lead to persistent disease and cause disability and serious consequences for the human population health status.

1. SEM image of Coxiella burnetii cell culture

2. How to recognize the Q-fever infection?

The main mammalian sources of Coxiella burnetii are ruminants – goats, sheep, cattle. The disease has been reported in almost all regions, except in New Zealand. The epidemiological levels of Q fever highly vary for the different countries and it depends on the geographic area and endemic profile. Scientists focused on the disease in 1999. Then, in The United States, the spread of the disease had led to 250% more cases of infected people in the period of 2000-2004. In Martigues (France), every 34 citizens from 100 000 were diagnosed with Q fever. More than 4000 cases were reported in The Netherlands between 2007 and 2010. An epidemic situation occurred in French Guiana due to the high virulence and stability of Coxiella burnetii cells. Normally, Q fever is not an acute disease and it is observed with flu-like symptoms. Most people infected with Coxiella burnetii have no symptoms at all.

However, there are cases of patients who get ill years after the infection. This is a result of an acute Q fever that can damage lungs, heart, liver. Q fever can be transmitted from animals to humans through urine, feces, milk and via inhalation of Coxiella burnetii-contaminated barnyard dust particles. The risk from infection is highest for groups like farmers, vets and researchers in field of veterinarian medicine and animal care. Q fever is cured quickly with antibiotic therapy but sometimes the treatment could take up to 1,5 years.

The symptoms occur between 3 and 30 days after exposure to Coxiella burnetii and may include high fever (more than 39 degrees Celsius), vomiting, cough, nausea, chills, fatigue, diarrhea, sensitivity to light.

Along with the location in a farm or near to farms or farming facilities, another risky factor is the time of the year – highest numbers of acute Q fever infected people are reported in April and May in The United States. Some reports show that the men are more likely to develop acute Q fever symptoms than women.

The risk of developing the acute form of Q fever (sometimes with lethal end) is higher for people with heart valve disease, weakened immune system, damaged kidney function, complications. The deadliest complication as a result of a Q fever recurrence is endocarditis. Q fever infected people can also develop pneumonia and acute respiratory distress. Pregnant women with chronic Q fever could have problems like low birth weight, premature birth or miscarriage. Other complications are observed with livers – people could have hepatitis due to Q fever infection, and brain meningitis – an inflammation of the membrane surrounding the brain and spinal cord.

2. X-ray image of a patient with pneumonia as a complication after Q

The prevention from Q fever includes vaccination for people who live in high-risk locations. The vaccine has been developed in Australia, 1989. The infection with Coxiella burnetii can be avoided with a consummation of pasteurized milk and pasteurized milk products only.

3. Which are the techniques used for diagnosis of Q fever?

The reference technique for detection of Coxiella burnetii is Indirect immunofluorescence assay (IFA) but other serology methods as complement fixation test (CFT) and ELISA are also used. Only kits and reagents for these assays are available on the market. ELISA has several advantages because it is easy to perform, the assay can be automated, and it is mainly used for diagnosis of acute and chronic Q fever. The most sensitive technique was IFA for detection IgM antibodies at an early phase of infection and after 12 months of follow-up. The sensitivity of CFT is reported as too low to be used for diagnosis and follow-up of C. burnetii persistent infection.

Several PCR-based analyses have been developed for the detection of Coxiella burnetii in clinical samples. The first standard PCR systems amplified plasmid sequences, the 16S-23S RNA, the superoxide dismutase gene, the com1 gene or the IS1111 repetitive elements in human or animal samples. Real-time PCR/qPCR is reported as faster and more sensitive PCR technique that provides information for the bacterium quantity in the tested clinical samples. Due to this, the qPCR assay is the most frequently used for detection of Coxiella burnetii these days. It targets IS1111 and can detect the bacterium within 2 weeks after exposure. Real-time PCR is also used for detection of persisting Coxiella burnetii infection in patients’ blood samples. The isolation and culturing of Coxiella burnetii is still used in many clinics and it can be achieved through the shell vial technique.

A new and interesting tool for detection of this pathogen is Immuno-PCR technique. It combines the PCR amplification with ELISA’s specificity and versatility which results in higher sensitivity. Many studies report that Immuno-PCR has significantly better sensitivity than ELISA and IFA in serum samples collected during the first 2 weeks after the symptoms’ development.

  Nowadays, the scientists are mainly focused on understanding the factors that could decrease the virulence of Coxiella burnetii. This will allow the development of effective strategies for treatment and prevention of Q fever and avoid the risk from complications such as endocarditis, hepatitis and pneumonia in patients from all over the world.